By Jonathan Bard (auth.), Albert Burger BSc, MSc, PhD, Duncan Davidson BSc, PhD, Richard Baldock BSc, PhD (eds.)
Bioinformatics as a self-discipline has come of age, and there at the moment are a variety of databases and instruments which are common via researchers within the biomedical box. in spite of the fact that, winning improvement of destiny bioinformatics functions is determined by an competently formalised illustration of area knowledge.
This e-book offers a well timed and first-of-its-kind choice of contributed chapters on anatomy ontologies. it truly is interdisciplinary in its procedure, bringing jointly correct services from computing and biomedical stories, and protecting either theoretical and utilized facets, with an emphasis on more recent paintings correct to the rising Semantic Web.
Topics and Features:
• offers a entire dialogue of the rules of anatomical ontologies and the cutting-edge in latest computational instruments and applications
• Considers a couple of basic modelling principles
• comprises chapters approximately learn on algorithms to systematically align anatomy ontologies and to mine facts within the literature, utilizing anatomy terms
• Explains fresh efforts to enhance a typical anatomy reference ontology
• Discusses anatomy within the context of spatio-temporal biomedical atlases
• Describes platforms and instruments for linking anatomy ontologies with one another and with different online assets, similar to the biomedical literature
• Highlights the demanding situations of facing anatomy-based info at the Semantic Web
Although basically written for readers who can be interested by constructing the following new release of IT purposes within the components of lifestyles sciences, biomedical sciences and well-being care, this particular quantity could be of curiosity to a person who will extra enhance anatomy ontologies, who will use them, and who could be fascinated about the particular improvement of appropriate (semantic) internet applications.
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Extra resources for Anatomy Ontologies for Bioinformatics: Principles and Practice
For example the exact relation between disorder and anatomy is different in “pneumonia”, “pleuridinia”, “intestinal obstruction”, and “cholelithiasis”; however, the differences are not consistently reﬂected in language, and each condition would normally be classiﬁed under disorders of the anatomical structures involved. 2 The fundamental relation of anatomy is the part-whole relation – the foot is part of the lower extremity; the ventricle is part of the heart, etc. The key pattern for clinical anatomy relates “locus” and “partonomy”.
The team that created PSO consisted of database curators and plant scientists, all experimental biologists by training. As expected, our main focus was the biological content of the ontology and the very pragmatic goal of providing a practical framework for annotations. The formal philosophical ontological rules and software implementations have been, to a large extent, neglected. The range of problems this approach created is similar to those described for some other informal bio-ontologies such as GO .
Stein, and S. McCouch. Gramene: a bird’s eye view of cereal genomes. Nucleic Acids Res, 34:D717–23, 2006. 16. J. Lawrence, Q. L. E. Seigfried, and V. Brendel. MaizeGDB, the community database for maize genetics and genomics. Nucleic Acids Res, 32:D393–397, 2004. 17. C. Mungall. Obol: Integrating language and meaning in bio-ontologies. Comp Funct Genom, 5:509–520, 2004. 18. Plant Ontology Consortium. The Plant Ontology Consortium and Plant Ontologies. Comp Funct Genom, 3:137–142, 2002. 19. A. Pujar, P.
Anatomy Ontologies for Bioinformatics: Principles and Practice by Jonathan Bard (auth.), Albert Burger BSc, MSc, PhD, Duncan Davidson BSc, PhD, Richard Baldock BSc, PhD (eds.)